Spray the bottom and sides of 6-quart slow-cooker crock with non-stick cooking spray.
Generously season the beef with salt and pepper on all sides and place in slow cooker crock. Add all remaining ingredients, cover, and cook on low for at least 8 hours.
When done cooking, remove the lid and shred beef with two forks while still inside the slow cooker. Allow shredded beef to marinate in warm cooking juices for 5 minutes to absorb more flavor.
Transfer shredded beef from slow cooker to a serving platter with tongs, allowing excess liquid to drain.
Top with chopped cilantro and serve immediately with fresh lime wedges and additional cooking juices on the side, if desired. Enjoy!
Notes
Tip: For best results, allow meat to cook on low for at least 8 hours.